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These findings indicated that the combination of (-)-Vestitol and Salviolone had synergistic effects on reducing both the A plaque burden and toxic soluble A levels in the cortex and hippocampus of APP/PS1 transgenic mice

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Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo

Likewise, the higher the dose, the greater the likelihood of damage

First, it would appear that gut dysbiosis is a cause and consequence of CNS pathology and hence creates self-propelling loops among inflammation, immune activation, and barrier dysfunction